Publications – (주)케마스

Korean

Publications

We believe in the value of collaboration, particularly to achieve our goal of continuing to develop breakthrough treatments for cancer and other diseases. We are looking for partnership opportunities with doctors, scientists, companies, and organizations in the industry and we always welcome discussions for collaboration. If you are interested in joint research, partnership, business opportunities etc, please contact: info@chemas.co.kr

Tetraarsenic oxide affects non-coding RNA transcriptome through deregulating polycomb complexes in MCF7 cells. Advances in Biological Regulation. 2021

Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells. Cell Death & Disease. 2021

Arsenic hexoxide has differential effects on cell proliferation and genome-wide gene expression in human primary mammary epithelial and MCF7 cells. Scientific Reports. 2021

Anti-Cancer Activity of As4O6 and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer. Pharmaceutics. 2020

Anticancer Efficacy of As4O6 in 5637 Human Bladder Cancer Cell Line. Ajou University. 2019

Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells. Plos ONE. 2017

Inhibition of STAT3/VEGF/CDK2 axis signaling is critically involved in the antiangiogenic and apoptotic effects of arsenic herbal mixture PROS in non-small lung cancer cells. Oncotarget. 2017

Effects of Tetra-arsenic Oxide on Proliferation, Migration and Invasion of Human Breast Cancer MCF-7 Cells. Chinese Journal of Information on TCM. 2017

HER-2/EGFR, the major targets for anti-metastasis effect of tetraarsenic oxide on SKBR3 breast cancer cells. Journal of Chinese Pharmaceutical Sciences. 2017

Tetraarsenic hexoxide demonstrates anticancer activity at least in part through suppression of NF-KB activity in SW620 human colon cancer cells. Oncology Reports. 2015

Tetraarsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation. Journal of Neurosurgery. 2014

Arsenic hexoxide enhances TNF-α-induced anticancer effects by inhibiting NF-KB activity at a safe dose in MCF-7 human breast cancer cells. Oncology Reports. 2014

Therapeutic efficacy of tetraarsenic hexoxide (As4O6) in the treatment of acute promyelocytic leukemia in animal model. 2013

Tetraarsenic oxide and cisplatin induce apoptotic synergism in cervical cancer. Oncology Reports. 2013

Tetraarsenic Hexoxide Demonstrates Anticancer Activities at Least in Part through Suppression of NF-kB-mediated Cellular Responses in Hep3B Human Hepatocellular Carcinoma Cells. Cancer prevention research. 2012

Tetraarsenic hexoxide Induces Beclin-1-Induced autophagic cell death as well as caspase-dependent apoptosis in U937 human leukemic cells. Evidence-Based Complementary and Alternative Medicine. 2012

Synergistic anti-tumor effects of combination of photodynamic therapy and arsenic compound in cervical cancer cells: in vivo and in vitro studies. PLoS One. 2012

Inhibition of cell growth and apoptosis in CaSki, cervical cancer cell line by arsenic compounds. Korean Journal of Obstetrics & Gynecology. 2010

Anti-tumor effect by Tetra-arsenic oxide in animal model implanted with cervical cancer cell line. 2010

Synergistic interaction between tetra-arsenic oxide and paclitaxel in human cancer cells in vitro. International Journal of Oncology. 2009

Tetra-arsenic oxide(TetraAs) enhances radiation sensitivity of solid tumors by anti-vascular effect. Cancer Letters. 2009

Vascular shutdown effects by tetraarsenic oxide in TC-1 cells implanted C57BL/6 mice. Korean Journal of Obstetrics and Gynecology. 2009

Anti-proliferative effect of tetra-arsenic Oxide (TetraAs) in human gastric cancer cells in vitro. Journal of Pharmaceutical Investigation. 2007

Comparison of diarsenic oxide and tetraarsenic oxide on anticancer effects: Relation to the apoptosis molecular pathway. International Journal of Oncology. 2007

Inhibitory effects of tetraarsenic oxide on the growth and metastasis of gastric cancer in SCID mice. Chinese Journal of Experimental Surgery. 2007

Apoptosis-induced cell growth inhibitory effects of a novel compound, As4O6 in a cervical cancer cell line, SiHa in vitro. Journal of Korean Association of Cancer Prevention. 2006

Pharmacokinetics of Arsenic Hexaoxide, a Anticancer Compound, in Rats. Journal of Pharmaceutical Investigation. 2006

Diarsenic and tetraarsenic oxide inhibit cell cycle progression and bFGF- and VEGF-induced proliferation of human endothelial cells. Journal of Cellular Biochemistry. 2005

Anti-angiogenic effect of As4O6 on the angiogenesis Induced by vascular endothelial growth Factor (VEGF) in the Rat Cornea. Journal of Veterinary Clinics. 2005

Reverse effects of tetra-arsenic oxide on the angiogenesis induced by nerve growth factor in the rat cornea. Journal of Veterinary Medical Science. 2004

Comparison of effects of As2O3 and As4O6 on cell growth inhibition and gene expression profiles by cDNA microarray analysis in SiHa cells. Oncology Reports. 2004

Tetraarsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway. International Journal of Oncology. 2003

Tetraarsenic oxide, a novel orally administrable angiogenesis inhibitor. International Journal of Oncology. 2003

The Gene Expression Profile Using cDNA microarray after treatment arsenic compound (As2O3, As4O6) in SiHa Cell. Korean Journal of Obstetrics and Gynecology. 2002